Review of the Literature: Cannabinoids as novel anti-inflammatory drugs
This is not your grandpa’s pot……
Cannabis, commonly known as marijuana, weed, pot, hash etc. is a product of the Cannabis sativa plant and the active compounds from this plant are collectively referred to as cannabinoids.
In the past hundreds of years marijuana has been used as a holistic treatment and its beneficial effects can be seen in treatment of nausea and vomiting associated with cancer chemotherapy; anorexia and cachexia seen in HIV/AIDS patients; and in neuropathic pain and spasticity in multiple sclerosis.
Cannabinoid pharmacology has made important advances in recent years after the discovery of the cannabinoid receptors (CB1 and CB2). Cannabinoids are a group of compounds that mediate their effects through cannabinoid receptors.
Cannabinoid receptors include CB1, which is predominantly expressed in the brain, and CB2, which is primarily found on the cells of the immune system. The fact that both CB1 and CB2 receptors have been found on immune cells suggests that cannabinoids play an important role in the regulation of the immune system.
Furthermore, when CBD compounds bind to these receptors, dopamine is released providing a relieving euphoric feeling that has become very useful as a natural “pain killer”.
Cannabinoids also suppress the inflammatory response and subsequently reduce disease symptoms.
For more info check out this article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/
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